Amodis 400mg (240pcs box)

Indications

Amodis 400 is an antibiotic that aids your body's defenses against bacterial and parasitic infections. Metronidazole is used to treat the following conditions:

The prevention of anaerobic bacteria-related post-operative infections (particularly species of Bacteroides and anaerobic streptococci).
Anaerobe-caused septicemia, bacteremia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, and post-operative wound infections.
When treating urogenital trichomoniasis.
Vaginosis is caused by bacteria (also known as non-specific vaginitis).
Amoebiasis in all its forms (intestinal, extra-intestinal disease, and symptomless cyst passers).
Giardiasis.
Gingivitis with acute ulceration.
Leg ulcers and pressure sores are caused by anaerobic bacteria.
Anaerobic organisms cause acute dental infections.
Pseudomembranous colitis caused by antibiotics

Pharmacology

Metronidazole is an antiprotozoal medication that belongs to the imidazole class of antibacterial drugs. Metronidazole's 5 nitro group is reduced by anaerobic bacteria metabolism. According to research, the reduced form of this drug interacts with DNA and produces metronidazole's bactericidal effect.

Dosage & Administration

Tablet and Suspension:

Trichomoniasis (Adults & Children over 10 yrs) (Adults & Children over 10 yrs) - 400 mg bid for 7 days, or 200 mg tid.
For two days, take 800 mg in the morning and 1-2 gm at night.
1 day of a single dose of 2 grams
Trichomoniasis (Children) (Children)
- Children 7 to 10 years old: 100 mg twice daily
Kids aged 3 to 7: 100 mg twice daily
50 mg twice daily for kids aged 1-3.
Amoebic enteritis (Adults & Children over 10 yrs)
- 800 mg five days per day
Amoebic enteritis (Children)
- Children 7 to 10 years old: 400 mg twice daily
200 mg qid for children ages 3 to 7
200 mg twice daily for kids aged 1-3.
Asymptomatic extra-intestinal amoebiasis (Adults & Children over 10 yrs)
- 400–800 mg once daily for 5–10 days.
Children with extra-intestinal and asymptomatic amoebiasis

Kids aged 7 to 10: 200–400 mg twice daily
100–200 mg qid for children aged 3–7 years.
100-200 mg tid for children ages 1-3

Adults and children over the age of 10 who have giardiasis

once everyday for three days, 2 gram

Children's Giardiasis

Children aged 7 to 10: 1 gram once a day
Children ages 3 to 7: 600 to 800 mg once daily
1-3 years old children: 500 mg once daily

Adults and children older than 10 years who have acute ulcerative gingivitis:

tid for 3 days at 200 mg

Children's acute ulcerative gingivitis

Kids aged 7 to 10: 100 mg twice daily
Kids aged 3 to 7: 100 mg twice daily
50 mg twice daily for kids aged 1-3.

Acute dental infections in adults and kids older than 10 years:

tid for 3–7 days at 200 mg

Adults and children over the age of 10 who have bacterial vaginosis:

400 mg once daily for 7 days
a single dose of 2 gm for 1day

Pressure sores and leg ulcers (Adults and Children Over 10 Years)

tid for seven days at 400 mg

Anaerobic infections in adults and kids older than 10 years:

800 mg at first, then 400 mg every day for seven days.

Children's anaerobic infections

7.5 mg/kg tid for children aged 1 to 10

Surgery prevention (adults and children older than 10 years):

400 mg tid for one day beginning 24 hours before surgery

Surgery prevention (for children):

7.5 mg/kg tid for children aged 1 to 10

Contraindications

Patients who have a history of allergy to metronidazole or other nitroimidazole derivatives should not use metronidazole.

Side Effects
Metallic smell, nausea, vomiting, diarrhea, drowsiness, and rash may occur during treatment.

Pregnancy & Lactation

The US FDA classifies pregnancy with metronidazole as B. However, there are no adequate and well-controlled studies on pregnant women. Because animal reproduction studies do not always predict human response, the drug should be used during pregnancy only when clearly necessary. Metronidazole has been shown to be excreted in human milk. Therefore, caution should be exercised when administering metronidazole to lactating women.

Warnings & Precautions
It is advised to perform hematological tests, particularly white blood cell counts, and monitor the patient for adverse reactions like peripheral or central neuropathy (such as feeling abnormal., Ataxia, dizziness, and seizures), if metronidazole must be administered for a longer period of time than is typically recommended.
Patients with hepatic encephalopathy should use metronidazole cautiously.
Patients should be made aware that metronidazole can cause their urine to turn black.

Storage Conditions

Store below 30°C. Keep protected from light. Keep medicines out of the reach of children. Do not use it later than the date of expiry.